1
Department of Radiology, Islamic Azad University, Mashhad Branch
2
Genetics Department, Islamic Azad University, Mashhad Branch
3
Islamic Azad University, Mashhad Branch
10.22034/icrj.2020.100850
Abstract
Background:
NT measurement is an ultrasonographic non-invasive
screening method at 11-14 weeks of gestation. Fetuses with increased NT are at higher risk of genetic disorders and structural defects. CGH array is one of the most recent methods for detecting chromosomal abnormalities, which is even more accurate than karyotype. Purpose:
We managed this study to evaluate fetal consequences in pregnancies with increased nuchal translucency and normal CGH array.
Methods:
In a descriptive-analytical study, CVS was done for fetuses with higher than normal NT measurments. CVS samples were evaluated with CGH array. Fetuses with normal CGH array results were followed for fetal outcomes with advanced anomaly scan at the 18th weeks of pregnancy and also neonatal checkup after birth.
Results:
78 pregnant women were included in our study.Ten fetuses (12.8%) showed abnormal chromosomal patterns. In the remaining fetuses (68 cases), we found 2 cases (2.9%) with congenital heart disorders and 8 cases (11.8%) with non-cardiac structural disorders. There were also 2 cases (2.9%) with intrauterine fetal death. There was no significant relationship between the age of pregnant mothers and the incidence of fetal complications (P value> 0.05).
Conclusions:
This study showed although chromosomal studies in fetuses with increased NT is of a great importance, ultrasonographic followup is mandatory.
Hashemi Attar, A., Ghayoor Karimiani, E., & Hamidi, F. (2019). A FETAL CONSEQUENCES OF PREGNANCIES WITH INCREASED NUCHAL TRANSLUCENCY AND NORMAL CGH ARRAY. Iranian Congress of Radiology, 35(3), 86-86. doi: 10.22034/icrj.2020.100850
MLA
Amirhossein Hashemi Attar; Ehsan Ghayoor Karimiani; Fatemeh Hamidi. "A FETAL CONSEQUENCES OF PREGNANCIES WITH INCREASED NUCHAL TRANSLUCENCY AND NORMAL CGH ARRAY". Iranian Congress of Radiology, 35, 3, 2019, 86-86. doi: 10.22034/icrj.2020.100850
HARVARD
Hashemi Attar, A., Ghayoor Karimiani, E., Hamidi, F. (2019). 'A FETAL CONSEQUENCES OF PREGNANCIES WITH INCREASED NUCHAL TRANSLUCENCY AND NORMAL CGH ARRAY', Iranian Congress of Radiology, 35(3), pp. 86-86. doi: 10.22034/icrj.2020.100850
VANCOUVER
Hashemi Attar, A., Ghayoor Karimiani, E., Hamidi, F. A FETAL CONSEQUENCES OF PREGNANCIES WITH INCREASED NUCHAL TRANSLUCENCY AND NORMAL CGH ARRAY. Iranian Congress of Radiology, 2019; 35(3): 86-86. doi: 10.22034/icrj.2020.100850
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