%0 Journal Article %T A FETAL CONSEQUENCES OF PREGNANCIES WITH INCREASED NUCHAL TRANSLUCENCY AND NORMAL CGH ARRAY %J Iranian Congress of Radiology %I Iranian Society of Radiology %Z 25885545 %A Hashemi Attar, Amirhossein %A Ghayoor Karimiani, Ehsan %A Hamidi, Fatemeh %D 2019 %\ 07/01/2019 %V 35 %N 3 %P 86-86 %! A FETAL CONSEQUENCES OF PREGNANCIES WITH INCREASED NUCHAL TRANSLUCENCY AND NORMAL CGH ARRAY %K Nuchal Translucency %K comparative genomic hybridization %K Chorionic Villus Sampling %K Ultrasonography %K Chromosomal abnormalities %R 10.22034/icrj.2020.100850 %X Background: NT measurement is an ultrasonographic non-invasive screening method at 11-14 weeks of gestation. Fetuses with increased NT are at higher risk of genetic disorders and structural defects. CGH array is one of the most recent methods for detecting chromosomal abnormalities, which is even more accurate than karyotype. Purpose: We managed this study to evaluate fetal consequences in pregnancies with increased nuchal translucency and normal CGH array.   Methods: In a descriptive-analytical study, CVS was done for fetuses with higher than normal NT measurments. CVS samples were evaluated with CGH array. Fetuses with normal CGH array results were followed for fetal outcomes with advanced anomaly scan at the 18th weeks of pregnancy and also neonatal checkup after birth.   Results: 78 pregnant women were included in our study.Ten fetuses (12.8%) showed abnormal chromosomal patterns. In the remaining fetuses (68 cases), we found 2 cases (2.9%) with congenital heart disorders and 8 cases (11.8%) with non-cardiac structural disorders. There were also 2 cases (2.9%) with intrauterine fetal death. There was no significant relationship between the age of pregnant mothers and the incidence of fetal complications (P value> 0.05).   Conclusions: This study showed although chromosomal studies in fetuses with increased NT is of a great importance, ultrasonographic followup is mandatory. %U