Hepatocellular Adenomas


MD, Assistant Professor of Radiology, Imam Khomeini Hospital, Tehran University of Medical Science


Hepatocellular adenomas are a heterogeneous group of tumors, which their potential complication  such as  evolving to hepatocellular carcinomas (HCC) and  hemorrhagic complications being closely linked to their molecular characteristics .
There are four molecular types of adenoma:
telangiectatic or inflammatory adenomas (40–50%),
adenomas with HNF1α mutations (20–40%),
adenomas with β catenin mutations (5–10%) and
non-specific adenomas (10–20%), with no molecular or phenotypic characteristic known to date
The MRI signs of adenomas appear to be correlated with their genotype in some of them and can be diagnosed by imaging