Different Magnetic Resonance Imaging Protocols for Multiple Sclerosis Diagnosis


1 MSc of Medical Imaging (MRI) HighTech Department Pars Hospital < alizadeh4949@gmail.com>

2 Tehran University of Medical Sciences < Amir.dareini.2000@gmail.com>



Multiple Sclerosis (MS) is a chronic autoimmune disease where the immune system wrongly attacks the central nervous and  is  characterized  pathologically  by
demyelination and clinically by visual, sensory, and motor problems. This immune-mediated disease is one of the most common causes of neurological disability in young adults
worldwide and currently is increasing in prevalence and incidence globally1.
Early and accurate diagnosis is of the utmost importance. Blood test, Spinal tap using lumbar puncture, Neurological exam and Magnetic Resonance imaging are the 4 common diagnostic tools for MS provident. MRI has a major role and is the most important available tool that supports the diagnosis and monitoring of MS. This review study was
aimed to evaluate different sequences for MS diagnosis and discuss each protocol hallmark. Sequences contain Spin-Echo sequences, gradient echo    sequences,                  Susceptibility sequences, Magnetic Resonance Spectroscopy, Magnetization transfer imaging, Diffusion Weighted imaging, USPIO sequences, and
some other modern sequences.
We discussed about characteristic hallmarks and each sequence-specific application