Investigating the Expression Level of Long Non-Coding RNAs in Response to Low-Dose Ionizing


1 Department of Radiobiology Iran University of Medical Sciences, Tehran, Iran.

2 Department of Medical Genetics Iran University of Medical Sciences, School of Medicine, Tehran,Iran. Iranian Biological resources center, Tehran, Iran.

3 Department of Radiation Science Faculty of Allied Medicine, Iran University of Medical Sciences,Tehran, Iran.

4 Department of Medical Genetics Faculty of Medical Sciences, Tarbiat Modares University, Tehran,Iran.

5 Radiation Biology Research Center Iran University of Medical Sciences, Tehran, Iran.



Despite the growing number of studies on lncRNAs, particularly in cancer biology, there is a lack of information about their specific roles. In this study, we evaluated the expression levels of LNCs after exposure to X-ray radiation and found that ANRIL was overexpressed in response to 8Gy radiation. Apoptosis, cell cycle and DNA repair-related LNCs may be promising avenues for further exploration of the effects of low-dose radiation and the cell sensitivity it may represent.