Correlation between Heart and Liver Iron Overload Measured by MRI T2* and Ferritin Level among Sistan and Baluchistan Thalassemia Major Patients


1 MSC of Medical Imaging Department of Radiology, Faculty Member of ParaMedicine, Zahedan University of Medical Science, Zaheden, Iran

2 Department of Radiology Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran

3 Zahedan University of Medical Sciences*

4 Zahedan University of Medical Sciences



This study investigated the correlation between Iron overload (IOL) in liver and heart as measured by Magnetic Resonance Imaging (MRI) T2* relaxation time technique and
serum ferritin levels in beta thalassemia major patients in Sistan and Baluchistan province as the population of Beta thalassemia major patients is higher in this province compared to rest of Iran. Methods: This cross-sectional study
was conducted at Ali Ibn Abi Taleb hospital in Zahedan, The MRI T2* data of liver and heart and ferritin serum levels were collected from 115 beta thalassemia major patients’ history.
There was a moderate correlation between the MRI T2* and serum ferritin levels, indicating that MRI T2* could be used to effectively monitor iron status in beta thalassemia major patients.
The results of this study suggest that MRI T2* technique could be a valuable, non- invasive tool for monitoring iron status in the beta thalassemia major patients.