High Resolution Computed Tomography (HRCT) in Patients with or Suspected of COVID-19: Determination of Effective Dose and Cancer Risk


1 Department of Medical Physics School of Medicine, Tabriz University of Medical Science, Tabriz, Iran*

2 Department of Medical Physics Kermanshah University of Medical Sciences, kermanshah, Iran

3 Department of Medical Physics School of Medicine, Tabriz University of Medical Science, Tabriz, Iran

4 Department of Medical Physics Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran

5 Clinical Research Development Center Shahid Modarres Educational Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran

6 Department of Medical Physics Associate Professor of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran)



The increasing prevalence of coronavirus has led to an increase in the use of CT scan, which is a high exposure imaging technique to follow the treatment in these patients. Therefore, this study was designed in order to estimate organ dose and effective dose to investigate the lifetime attributable risks (LARs) of cancer incidence and cancer- related mortality in patients with or suspected of covid-19.
Material and Methods:
A total of 600 patients with or suspected of COVID-19 participated voluntarily in this study. To estimate the cancer risk, some dosimetric parameters including dose length product(DLP), volumetric CT dose index (CTDIV), scan length, organ dose, and effective dose were used. ImPACT CT dosimetry software was also used for dose calculation
i.e. organs and effective doses; and the cancer risk estimation was done based on the 2006 National Academy of Sciences Biologic Effects of Ionizing Radiation (BEIR VII) report.
The mean age of men and women was
41.87 ± 14.16 and 38.96 ± 13.74, respectively (40.5% males and 59.5% females). The mean of effective dose in women based on international commission radiation protection 103 (ICRP103) and ICRP60 was 2.36 ± 0.48 msv and 1.2 ± 0.28 msv, respectively. In men, this parameter was 2.31 ± 0.53 msv and 1.21 ± 0.45 msv based on ICRP103 and ICRP60, respectively. The mean of LAR, incidence, and mortality of cancer in men was 6.45 ± 2.22 and 6.25 ± 2.22, respectively, and in women, these parameters were 22.6 ± 10 and 14.32 ± 4.91 per 100000 people.
Due to the high risk of cancer because of CT scan in people with or suspected of coronavirus, especially women due to the presence of breast tissue and thyroid sensitivity, the request of CT scan for these people should be done more carefully.
Keywords: Covid-19, Effective dose, High resolution computed topography, Risk of cancer incidence, Risk of cancer mortality