BREAST CANCER MOLECULAR SUBTYPE CORRELATION WITH SONOGRAPHY

Breast sonogram indication goes far not only for differentiation cystic or solid mass advanced solography of breast have ability to diagnosis malignant breast mass with high predictive value more than 95 %.
The multiple features of malignant masses such as speculation, angular margin, posterior acoustic shadow, branching, vascularity and shape could  help us to diagnosis luminal A, luminal B, her2 and  triple negative, the calcification help us to know out come of diseases and prognosis as well to choose  better managing of treatment, the 36  patient with proved  breast  cancer  biopsy  and subtype molecular calcification correlated  with breast mass malignant features  in sonogram and find out, luminal A have angular border and echogenic halo, luminal B have angular shape with posterior shadow and hyper vascular pattern on doppler images HER2 have  angular margin and posterior enhancement and triple negative have oval shape and microloublation  with at least  85% accuracy.
how ever this calcification based on estrogen, progesterone and her 2 (epidermal growth factor) receptors, which have significant role on prognosis and endocrine therapy, chemotherapy, and type of surgery.