@article { author = {Abbasi, Bita and Shams, Majid and Farrokh, Donya and Zandi, Behrooz and Pezeshki-Rad, Masoud and Hashemi, Jahanbakhsh and Feyzi Laein, Ali and Tayebi, Shamim}, title = {DIAGNOSTIC VALUE OF VENOUS -ARTERIAL ATTENUATION RATIO AND HOUNSFIELD-HEMATOCRIT RATIO IN THE EVALUATION OF ACUTE CEREBRAL VENOUS SINUS THROMBOSIS IN NON-CONTRAST BRAIN COMPUTED TOMOGRAPHY}, journal = {Iranian Congress of Radiology}, volume = {35}, number = {3}, pages = {87-87}, year = {2019}, publisher = {Iranian Society of Radiology}, issn = {25885545}, eissn = {25885545}, doi = {10.22034/icrj.2020.100851}, abstract = {Background: Elevated density of the venous sinuses is a typical sign of cerebral venous sinus thrombosis (CVST) on non-contrast brain computed tomography (NCBCT). The purpose of this study was to assess the diagnostic value of V:A and H:H ratios for diagnosis of acute CVST in NBCT.   Materials and Methods: This retrospective case-control study included 50 confirmed cases of patients with CVST by using contrast-enhanced MR venography and 73 cases age- and sex-matched without CVST. Two blinded experienced observers independently  interpreted the images for the presence of acute CVST and obtained attenuation values and V:A and H:H ratios for thrombosed and non-thrombosed sinuses on brain NCCT.   Results: A   significant   difference   in   the   average   sinus attenuation was found between patients with acute cerebral venous sinus thrombosis (65.8±6.4 HU) and the control group (44.9±6.2 HU; P < .0001).    A similar difference was found for the H:H ratio (1.69±0.32 vs 1.25 ± 0.25) and V:A ratio (2.07±0.55 vs 1.1±0.2) in patients with and without CVST, respectively; (P < .0001). Optimal thresholds of 55 HU lead to sensitivities of 92% and specificities of 96% for average sinus attenuation and 1.37 lead to sensitivities of 88% and specificities of 77% for the H:H ratio and 1.43 lead to sensitivities of 100% and specificities of 93.8% for the V:A ratio.   Conclusions: Increased attenuation and the H:H ratio and V:A ratio in the dural sinuses on non-contrast brain computed tomography have a high sensitivity and specificity in diagnosis of acute cerebral venous sinus thrombosis.}, keywords = {Cerebral venous sinus thrombosis (CVST),Non- contrast brain computed tomography (NCBCT),Venous arterial attenuation ratio (V:A ratio),Honsfield-hematocrit ratio (H:H ratio)}, url = {https://www.icrjournal.ir/article_100851.html}, eprint = {} }