Measuring the Absorbed Dose of Gonads in Prostate Cancer Radiotherapy by Treatment Design and Dosimetry Software

Author

Sbmu < omidikiumars@yahoo.com>

10.22034/icrj.2023.179784

Abstract

Background and Purpose:
The effect of radiation in increasing the risk of cancer and its other harmful effects has been proven. The possibility of chromosomal damage and the creation of genetic mutations has also been proven as a result of damage to DNA, and it is one of the most important and fundamental damages of radiation. Gonads in men are among the most vulnerable parts when exposed to radiation. The present study was conducted to measure the absorbed dose of gonads in prostate cancer radiotherapy.
Methodology:
This study was an experimental scientific study in which the dose reached to the gonads in radiotherapy treatments for prostate cancer was investigated and calculated. The method of measuring the radiation transmission coefficient is to measure the absorbed dose of radiation at a certain point, with and without a shield, and this coefficient is obtained by dividing the value read with the shield by the one without the shield. The amount of 70
times of radiation in this study was done with the medical linear accelerator device available (Varian X linear accelerator with MV18 photon energy), 40 times of which was by TLD chips and 30 times by the ionization chamber. Farmer type was used.
Findings:
The radiation passing through cedar blocks that was measured in this research was equal to 4%. The absorbed dose resulting from the scattering of the collimator on the head of the patient’s body, etc., which in this research was between 3 and 5% in different conditions. The target was 4 to 6 percent.
Conclusion:
In the treatments of the abdominal region, the testicle is not in the radiotherapy field. But a significant absorbed dose of scattered rays reaches the testicle, which is up to 9.5%.
Keywords: radiation therapy; gonads; Prostate Cancer; Linear accelerator.