Iranian Congress of Radiology

Iranian Congress of Radiology

Investigating the Expression Level of Long Non-Coding RNAs in Response to Low-Dose Ionizing

Authors
Mohammad Ali Pourattar* 1
Morteza Talebi* 2
Reza Paydar 3
Hossein Mozdarani 4
Asghar Maziyar* 5
1 Department of Radiobiology Iran University of Medical Sciences, Tehran, Iran.
2 Department of Medical Genetics Iran University of Medical Sciences, School of Medicine, Tehran,Iran. Iranian Biological resources center, Tehran, Iran.
3 Department of Radiation Science Faculty of Allied Medicine, Iran University of Medical Sciences,Tehran, Iran.
4 Department of Medical Genetics Faculty of Medical Sciences, Tarbiat Modares University, Tehran,Iran.
5 Radiation Biology Research Center Iran University of Medical Sciences, Tehran, Iran.
10.22034/icrj.2023.179577
Abstract
 
Introduction:
Despite the growing number of studies on lncRNAs, particularly in cancer biology, there is a lack of information about their specific roles. In this study, we evaluated the expression levels of LNCs after exposure to X-ray radiation and found that ANRIL was overexpressed in response to 8Gy radiation. Apoptosis, cell cycle and DNA repair-related LNCs may be promising avenues for further exploration of the effects of low-dose radiation and the cell sensitivity it may represent.
Iranian Congress of Radiology
Volume 38, Issue 4
Autumn 2023
Pages 182-182

  • Receive Date 20 September 2023