Purpose:
Preeclampsia is a pregnancy related endothelial malfunction with rapid raise in blood pressure and proteinuria which develops during pregnancy (typically begins after 20 weeks of pregnancy). This study aims at investigating the predictive power of the intima-media thickness of the uterine artery (UA-IMT) in prognosticating preeclampsia.
Methods:
This observational single-center investigation was conducted on 60 female participant in three subgroups of 20 (preeclamptic, healthy pregnant, and non-pregnant women with normal blood pressure). The average value of the UA-IMT, measured in 3 standard predefined areas of the uterine artery on both sides, were assessed implementing a 3-5 Mhz curved probe. The mean UA-IMT was then compared between the three study subgroups. Mechanical and thermal indices were kept below standard values, and tissue harmonic function was turned-on during all exams. Ultrasound beam focus was set immediately superficial to the uterine artery near wall.
Results:
The mean UA-IMT in preeclamptic, healthy pregnant and non-pregnant women were measured at 237.75±19.83 µm (ranging from 210 To 290 µm), 231.50± 20.14 µm (ranging from 195 To 275 µm), And 244.50 ± 34.75 µm (ranging from 195 to 310 µm), respectively. Although the mean value was lower in healthy pregnant women, the difference was not significant (P = 0.290).
Conclusion:
UA-IMT was not significantly different between the study subgroups, thus it cannot predict or detect preeclampsia where suspicion raises clinically.