TO DETERMINE THE DIAGNOSTIC VALUE OF FIRST TRIMESTER UTERINE ARTERY PI FOR PREDICTION OF ABORTION OR IUFD

Background:
Doppler technique is a non-invasive method to study uterine perfusion. Inadequate uterine artery flow can disrupt the fetal replacement process. Inadequate uterine perfusion, regardless of etiological factors, is another important factor in spontaneous abortion in women. Uterine blood flow resistance is higher in the mid-luteal phase of patients with recurrent miscarriage than in normal individuals. Doppler studies in patients at risk of miscarriage have shown different results. The aim of this study was to evaluate the diagnostic value of PI index in the first trimester of pregnancy in predicting pregnancy outcomes.
Materials and Methods:
The present study is a cross-sectional study. In this study, 191 pregnant women in the 11th-13th week of pregnancy referred to the teaching hospitals of Shiraz University of Medical Sciences were selected and examined. Data were collected using a checklist. This checklist had two parts. The first part was the data related to ultrasound findings in week 11-13 and follow-up ultrasound and in the second part the findings related to pregnancy outcome including abortion, gestational hypertension, gestational glucose, stillbirth and IURG were recorded and used by SPSS software. And independent t-test, chi-square were analyzed.
Results:
143 patients (74.9%) had no history of abortion and 48 patients (25.1%) had  history of abortion. 16 patients (8.4%) had high blood pressure, 9 patients (4.7%) had blood sugar, 6 patients (3.1%) had pregnancy poisoning, 15 patients (7.9%) had intrauterine growth restriction and 4 patients (1 / 2%) had fetal death. The mean PI in mothers with fetal death and mothers with intrauterine growth restriction was significantly higher than mothers who did not have a history of fetal death and intrauterine growth restriction (P <0.05). The results of the table also showed that the difference between the mean PI in mothers with and without abortion, blood pressure, blood sugar, pregnancy poisoning was not statistically significant (P> 0.05). Per unit increase in PI, the risk of IUGR in pregnant women was significantly 2.3 times (OR = 2.32) and the risk of fetal death in pregnant mothers was 5 times (OR = 5.06).
Conclusion:
In general, the results of the study showed that the mean PI in mothers with fetal death and mothers with intrauterine growth restriction was significantly higher than mothers who did not have a history of fetal death and intrauterine growth restriction. Improvement in PI index (arterial resistance Uterine) improves uterine blood flow and improves the outcome of pregnancy, especially reducing the risk of miscarriage.