Medical University of Isfahan
University of Esfahan
Uninersity of Isfahan Medical Sciences
The purpose of the present study was to determine the
diagnostic accuracy ofTransluminal attenuation gradient (TAG) in 64-slice multislice computed tomography in the detection of significant coronary artery disease, using diameter stenosis as the comparison. Methods:
In 82 patients scheduled for coronary CTangiography, 64-slice MSCT was performed and evaluated for the presence of significant (>50% luminal narrowing) stenosis. Then TAG determined from the change in HU per 5-mm length of coronary artery and defined as the linear regression coefficient between intra-HU and length from the ostium (millimeters).
Total mean (S.E) of TAG is -2.87(0.28), the TAG is significantly different (PV<0.0001) in patients with significant stenosis -4.71(0.36) in compare with nonsignificant stenosis -1.30(0.23). Also we definition the cutoff point for TAG for better evaluation of severity.
The present study confirms that TAG is the accurate and noninvasive functional method to determine the significant coronary artery stenosis.