Post treatment imaging of primary CNS tumors are challenging and most of the time necessitate advanced imaging techniques. Many treatment options are available to treat CNS neoplasms with different post treatment imaging presentation.It is critical to diagnosis and report the post treatment changes versus tumor recurrence/ progression correctly. In this presentation I am going to review the main post treatment changes and the way that the radiologists can differentiate them versus tumor progression. In addition to the anatomic imaging, the hybrid techniques will be discussed. The standard treatment response criteria will be discussed as well
