TY - JOUR ID - 100851 TI - DIAGNOSTIC VALUE OF VENOUS -ARTERIAL ATTENUATION RATIO AND HOUNSFIELD-HEMATOCRIT RATIO IN THE EVALUATION OF ACUTE CEREBRAL VENOUS SINUS THROMBOSIS IN NON-CONTRAST BRAIN COMPUTED TOMOGRAPHY JO - Iranian Congress of Radiology JA - ICRJ LA - en SN - AU - Abbasi, Bita AU - Shams, Majid AU - Farrokh, Donya AU - Zandi, Behrooz AU - Pezeshki-Rad, Masoud AU - Hashemi, Jahanbakhsh AU - Feyzi Laein, Ali AU - Tayebi, Shamim AD - Mashhad University of Medical Sciiences AD - Mashhad University of Medical Sciences AD - Mashhad University of Medical Science AD - Hashemi AD - (MUMS) Y1 - 2019 PY - 2019 VL - 35 IS - 3 SP - 87 EP - 87 KW - Cerebral venous sinus thrombosis (CVST) KW - Non- contrast brain computed tomography (NCBCT) KW - Venous arterial attenuation ratio (V:A ratio) KW - Honsfield-hematocrit ratio (H:H ratio) DO - 10.22034/icrj.2020.100851 N2 - Background: Elevated density of the venous sinuses is a typical sign of cerebral venous sinus thrombosis (CVST) on non-contrast brain computed tomography (NCBCT). The purpose of this study was to assess the diagnostic value of V:A and H:H ratios for diagnosis of acute CVST in NBCT.   Materials and Methods: This retrospective case-control study included 50 confirmed cases of patients with CVST by using contrast-enhanced MR venography and 73 cases age- and sex-matched without CVST. Two blinded experienced observers independently  interpreted the images for the presence of acute CVST and obtained attenuation values and V:A and H:H ratios for thrombosed and non-thrombosed sinuses on brain NCCT.   Results: A   significant   difference   in   the   average   sinus attenuation was found between patients with acute cerebral venous sinus thrombosis (65.8±6.4 HU) and the control group (44.9±6.2 HU; P < .0001).    A similar difference was found for the H:H ratio (1.69±0.32 vs 1.25 ± 0.25) and V:A ratio (2.07±0.55 vs 1.1±0.2) in patients with and without CVST, respectively; (P < .0001). Optimal thresholds of 55 HU lead to sensitivities of 92% and specificities of 96% for average sinus attenuation and 1.37 lead to sensitivities of 88% and specificities of 77% for the H:H ratio and 1.43 lead to sensitivities of 100% and specificities of 93.8% for the V:A ratio.   Conclusions: Increased attenuation and the H:H ratio and V:A ratio in the dural sinuses on non-contrast brain computed tomography have a high sensitivity and specificity in diagnosis of acute cerebral venous sinus thrombosis. UR - https://www.icrjournal.ir/article_100851.html L1 - ER -